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[II. Use of antibodies to DNA modified by trans-diaminodichloroplatinum, for identification of specific DNA
Molekuliarnaia Biologiia
|March 1, 1991
Abstract:
DNA modified by trans diaminedichlorplatinum-II (transDDP) has been suggested as an effective probe for non-isotopic hybridization and high-specific anti-DNA-transDDP antibodies with horse radish peroxidase or alkaline phosphotase conjugated antibodies to rabbit Ig and protein A-peroxidase - for hybrids visualization. This method allows to detect 2 pg/mm DNA.