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Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Jun 30, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

[Two- and three-dimensional, morphologic and functional MR-imaging in smelling disorders].

N Abolmaali1, T Hummel, M Damm

  • 1OncoRay - Strahlenforschung in der Onkologie, Molekulare und Biologische Bildgebung, Medizinische Fakultät Carl Gustav Carus, TU Dresden, Dresden, Germany. Nasreddin.Abolmaali@OncoRay.de

Laryngo- Rhino- Otologie
|September 25, 2008
PubMed
Summary

Olfactory dysfunction is common. Magnetic resonance imaging (MRI) offers key insights for diagnosis and evaluation, presenting recent standards in structural imaging techniques.

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Context:

  • Olfactory dysfunction is a frequent clinical diagnosis.
  • Structural neuroimaging is crucial for evaluating olfactory dysfunction.
  • Magnetic resonance imaging (MRI) is the primary tool for quantitative and qualitative assessment.

Purpose:

  • To review current standards in structural imaging for olfactory dysfunction.
  • To discuss the application of magnetic resonance imaging (MRI) techniques in clinical practice.
  • To present relevant MRI methods for patient workup and imaging evaluation.

Summary:

  • This overview focuses on recent advancements in structural imaging for olfactory dysfunction.
  • Magnetic resonance imaging (MRI) is highlighted as the most significant imaging modality.
  • The text details MRI techniques applicable in routine clinical settings and subsequent evaluations.

Impact:

  • Provides clinicians with updated information on imaging standards for olfactory dysfunction.
  • Facilitates better diagnostic accuracy and patient management through advanced MRI techniques.
  • Contributes to the understanding of structural changes associated with olfactory deficits.