Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
What is Gene Expression?01:42

What is Gene Expression?

Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and Safety of the Bruton's Tyrosine Kinase Inhibitor Evobrutinib in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Trial.

ACR open rheumatology·2022
Same author

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.

Nature immunology·2015
Same author

Behavioral Hyperventilation and Central Sleep Apnea in Two Children.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2015
Same author

TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.

The Journal of experimental medicine·2015
Same author

Linking acute infection to chronic lung disease. The role of IL-33-expressing epithelial progenitor cells.

Annals of the American Thoracic Society·2014
Same author

Myb permits multilineage airway epithelial cell differentiation.

Stem cells (Dayton, Ohio)·2014
Same journal

Overlapping Mechanisms and Novel Biomarkers Define Asthma and COPD as a Spectrum of Airway Disease.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Real-World Variation in Post-Dose Supervision and Activity Restriction During Maintenance Cow's Milk Oral Immunotherapy.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Small Airway Dysfunction and Prior Exacerbations are Common in Primarily Well-Controlled Pediatric Asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Elevated Absolute Eosinophil Counts are Associated with Hypertension, Coronary Heart Disease, and Stroke.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Pharmacokinetics and pharmacodynamics of AQST-109 sublingual film in oral allergy syndrome: A phase 2 study.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Biomarkers for COPD with Type 2 Inflammation.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
See all related articles

Related Experiment Video

Updated: Jun 30, 2026

Performing Custom MicroRNA Microarray Experiments
07:04

Performing Custom MicroRNA Microarray Experiments

Published on: October 28, 2011

Basic science for the practicing physician: gene expression microarrays.

Anand C Patel1

  • 1Division of Allergy/Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, 63110, USA. Patel_an@kids.wustl.edu

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|September 26, 2008
PubMed
Summary
This summary is machine-generated.

Gene expression microarray technology enables genome-wide gene measurement, advancing understanding of immunologic diseases. Microarray clinical tests are emerging, promising novel diagnostics for allergy and immunology physicians.

More Related Videos

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
09:27

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

Bacterial Gene Expression Analysis Using Microarrays
29:41

Bacterial Gene Expression Analysis Using Microarrays

Published on: May 28, 2007

Related Experiment Videos

Last Updated: Jun 30, 2026

Performing Custom MicroRNA Microarray Experiments
07:04

Performing Custom MicroRNA Microarray Experiments

Published on: October 28, 2011

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
09:27

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

Bacterial Gene Expression Analysis Using Microarrays
29:41

Bacterial Gene Expression Analysis Using Microarrays

Published on: May 28, 2007

Area of Science:

  • Molecular Biology
  • Immunology
  • Genomics

Background:

  • Gene expression microarray technology allows for the simultaneous measurement of thousands of genes.
  • This technology has revolutionized the study of complex biological processes and diseases.

Purpose of the Study:

  • To provide an overview of gene expression microarray technology.
  • To highlight its relevance and applications for physicians in allergy and immunology.

Main Methods:

  • A literature search of PubMed/MEDLINE was conducted for articles on gene expression microarrays.
  • Articles focusing on clinical applications and use in allergy, asthma, and immunologic diseases were prioritized.
  • Author's expertise supplemented the literature search.

Main Results:

  • Gene expression microarray technology enables comprehensive analysis of gene expression patterns across the genome.
  • This approach has significantly enhanced the understanding of immunologic mechanisms in various disease models.

Conclusions:

  • Microarray technology is a powerful tool for investigating the genetic underpinnings of allergic and immunologic diseases.
  • While initially a research tool, microarray-based clinical tests are becoming available, aiding in novel diagnostic development.
  • Future applications in allergy and immunology promise improved diagnostic capabilities and deeper insights into disease pathogenesis.