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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Left ventricular solid body rotation in non-compaction cardiomyopathy: a potential new objective and quantitative
Bas M van Dalen1, Kadir Caliskan, Osama I I Soliman
1Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.
European Journal of Heart Failure
|September 26, 2008
Summary
Left ventricular (LV) twist is altered in non-compaction cardiomyopathy (NCCM) patients, showing similar base and apex rotation. This "LV solid body rotation" may serve as a diagnostic criterion for NCCM.
Area of Science:
- Cardiology
- Cardiac Mechanics
- Medical Imaging
Background:
- Left ventricular (LV) twist arises from myocardial fiber interactions during cardiac development.
- Non-compaction cardiomyopathy (NCCM) is linked to disrupted myocardial development, potentially affecting LV twist.
- Altered LV twist in NCCM may be distinct from changes seen in other cardiomyopathies.
Purpose of the Study:
- To evaluate and compare LV twist characteristics in NCCM patients.
- To contrast NCCM findings with non-ischaemic dilated cardiomyopathy (DCM) and healthy controls.
Main Methods:
- Speckle tracking echocardiography was used to assess LV twist.
- Study included 10 NCCM patients, 10 DCM patients, and 10 healthy controls.
Main Results:
- Normal subjects and DCM patients exhibited typical LV twist (basal clockwise, apical counterclockwise rotation).
- All NCCM patients displayed synchronous rotation of the LV base and apex.
- This synchronous rotation represents "LV solid body rotation" with minimal LV twist.
Conclusions:
- LV solid body rotation is a potential new diagnostic marker for NCCM.
- This finding offers an objective, quantitative functional criterion for NCCM diagnosis.
- The distinct rotation pattern in NCCM differentiates it from DCM and normal hearts.
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