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Updated: Jun 30, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Aggressive organ donor management protocol.

Joseph DuBose¹, Ali Salim

¹Division of Trauma and Critical Care at the Los Angeles County and University of Southern California Medical Center, Los Angeles, California, USA.

Journal of Intensive Care Medicine

|September 26, 2008

Summary

This summary is machine-generated.

The organ shortage crisis requires optimizing organ donation. Standardized donor management protocols improve organ yield from brain-dead donors, increasing transplant availability.

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Pre-clinical Model of Cardiac Donation after Circulatory Death

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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Area of Science:

Transplantation Medicine
Public Health
Organ Donation Science

Background:

Over 96,900 individuals were on the organ transplant waiting list in the US as of August 2007.
The significant disparity between organ demand and supply contributes to a national public health crisis.
The Organ Donation Breakthrough Collaborative was initiated to address this critical organ shortage.

Purpose of the Study:

To evaluate strategies for increasing the number of available transplantable organs.
To investigate the impact of standardized donor management protocols on organ yield.
To reduce donor loss due to medical complications associated with brain death.

Main Methods:

Implementing standardized and aggressive donor management protocols for brain-dead donors.
Optimizing physiological conditions in donors to preserve organ viability.
Utilizing a dedicated organ donor management team for protocol-driven care.

Main Results:

Standardized donor management protocols have demonstrated an increase in the number of organs transplanted.
These protocols help prevent donor loss resulting from medical failures.
A protocol-driven approach enhances the efficiency of organ procurement.

Conclusions:

Optimizing donor management is crucial for maximizing organ recovery from the brain-dead donor pool.
Protocol-driven organ donor management is a key strategy to bridge the gap between organ supply and demand.
Implementing these protocols can significantly improve organ transplantation rates.