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Updated: Jun 30, 2026
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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive
Minseon Cho1, Min Su Han, Changill Ban
1Department of Chemistry, Pohang University of Science and Technology, Pohang, Gyeongbuk, 790-784, Republic of Korea. ciban@postech.ac.kr.
Chemical Communications (Cambridge, England)
|September 26, 2008
Abstract:
A gold nanoparticle-based competitive colorimetric assay can detect mismatched DNAs using MutS, a mismatch binding protein, and determine their relative binding affinities for this protein by a simple color change and the melting temperature of DNA-functionalized nanoparticle assemblies.
