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Updated: Feb 7, 2026
08:39
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
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Nutrition, total fluid and bladder cancer
Maree Brinkman1, Maurice P Zeegers
1Cancer Epidemiology Centre, The Cancer Council Victoria, Australia.
Scandinavian Journal of Urology and Nephrology. Supplementum
|December 5, 2008
Summary
Specific fruits and vegetables, like carrots, may reduce bladder cancer risk in older males. Conversely, salted meats and artificial sweeteners might increase risk, though fluid intake showed no clear association.
Area of Science:
- Epidemiology
- Nutritional Science
- Oncology
Background:
- Bladder cancer is a significant health issue, particularly for older males in Western countries.
- Early suggestions indicated a potential role for nutrition in bladder cancer etiology.
- Existing research presents inconsistent findings due to study heterogeneity.
Purpose of the Study:
- To provide an updated synthesis of scientific evidence on nutrition and fluid intake in relation to bladder cancer.
- To rank the strength of evidence for various dietary factors and fluid consumption.
- To identify potential protective and risk factors for bladder cancer.
Main Methods:
- Conducted a comprehensive literature search of major scientific databases (PubMed, ISI, Embase, Cochrane Library).
- Included epidemiological studies published from 1966 to October 2007.
- Ranked evidence based on statistically significant associations, relative risks, and mechanistic data.
Main Results:
- Fruits (especially citrus) and yellow-orange vegetables (like carrots) show probable/possible protective effects against bladder cancer.
- Selenium intake is also likely associated with reduced bladder cancer risk.
- Potential risk factors include salted/barbecued meats, pork, total fat, pickled vegetables, salt, soy products, spices, and artificial sweeteners.
Conclusions:
- Certain fruits and vegetables may play a role in reducing bladder cancer risk.
- Further research should focus on food categorization, quantity, and gender-specific effects in bladder cancer studies.
- No definitive association was found for beef, eggs, processed meats, or total fluid intake.
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