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Updated: Jun 30, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Bladder cancer: chemoprevention, complementary approaches and budgetary considerations
H Barton Grossman1, Arnulf Stenzl, Mark A Moyad
1University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. hbgrossman@mdanderson.org
Abstract:
Bladder cancer results from complex and only partially understood host-environmental interactions. Tobacco smoking is the greatest risk factor for bladder cancer, but the actual risk to an individual reflects not only the amount of exposure to the carcinogens in tobacco smoke but also host susceptibility to these carcinogens and possibly other factors. Lifestyle may have a significant effect on the incidence of this disease. The forms of chemoprevention and their relevance to bladder cancer, the impact of lifestyle and complementary medicine, and the costs of diagnosing and treating bladder cancer are reviewed to provide a base for advances in decreasing the incidence, recurrence and costs of this disease.
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