Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A full-active phosphorus dendron-based nanomedicine alleviates ischemic stroke through multi-target immunomodulation and neuroprotection.

Bioactive materials·2026
Same author

Fair priority setting in gene-editing research: the accountability for reasonableness framework.

EMBO molecular medicine·2026
Same author

A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis.

PloS one·2026
Same author

Bioactive hydroxyl-terminated phosphorus dendrimers mediate protein/drug co-delivery for enhanced multi-target ischemic stroke therapy.

Biomaterials·2026
Same author

Characterization of a Silver Vinylcarbene Intermediate in Carbene-Alkyne Metathesis and Its Concerted C(sp<sup>2</sup>)-H Bond Insertion.

Journal of the American Chemical Society·2026
Same author

Skeletal Rearrangement of Biaryls via Rhodium-Azirine Intermediate: A Route to Solid-State Emissive Polycyclic Sulfamates.

ACS catalysis·2026

Related Experiment Video

Updated: Jun 30, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
16:19

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

Cationic and fluorescent "Janus" dendrimers.

Sabine Fuchs1, Anna Pla-Quintana, Serge Mazères

  • 1Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse Cedex 4, France.

Organic Letters
|September 26, 2008
PubMed
Summary

Researchers synthesized Janus-type dendrimers with distinct ammonium and fluorescent dansyl groups. These novel surface-block dendrimers show potential as fluorescent labels in materials science and biology.

More Related Videos

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

Related Experiment Videos

Last Updated: Jun 30, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
16:19

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

Area of Science:

  • Supramolecular Chemistry
  • Materials Science
  • Organic Synthesis

Background:

  • Dendrimers offer unique nanoscale architectures with tunable properties.
  • Janus-type molecules, with distinct functionalities on opposite sides, are of growing interest.
  • Cyclotriphosphazene cores provide a versatile platform for constructing complex dendritic structures.

Purpose of the Study:

  • To develop synthetic methodologies for Janus-type dendrimers.
  • To characterize the structure and photophysical properties of these novel dendrimers.
  • To explore their potential applications as fluorescent labels.

Main Methods:

  • Synthesis of two distinct dendrons from a hexafunctional cyclotriphosphazene core.
  • Coupling of the synthesized dendrons to create surface-block Janus dendrimers.
  • Characterization using spectroscopic techniques and evaluation of photophysical behavior.

Main Results:

  • Successful synthesis of Janus-type dendrimers with ammonium and dansyl functionalities.
  • The largest synthesized dendrimer features 10 ammonium and 5 dansyl groups.
  • Demonstrated photophysical properties suitable for labeling applications.

Conclusions:

  • Established efficient synthetic routes to Janus-type dendrimers.
  • The synthesized dendrimers exhibit promising characteristics for use as fluorescent labels.
  • Potential applications in advanced materials and biological imaging are highlighted.