Related Experiment Video
Updated: Jun 30, 2026

Protocols for Quantifying Transferable Pesticide Residues in Turfgrass Systems
Published on: March 15, 2017
Kicking off the polo game
Frank Eckerdt1, James L Maller
1Howard Hughes Medical Institute and Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Abstract:
Polo-like kinase 1 (Plk1) is essential for checkpoint recovery and the activation of key mitotic enzymes; however, its own activation mechanism has remained elusive. Recent findings show that Bora, a G(2)-M expressed protein, facilitates Plk1 activation by the oncogenic kinase Aurora A in G(2). During mitosis, Plk1-dependent Bora degradation promotes Aurora A localization to the centrosome and/or spindle. Bora-dependent regulation provides important new insights into interactions between key mitotic kinases.
Related Concept Videos
Motion of a Projectile
Horizontal motion, governed by the initial kick, maintains a constant velocity throughout the flight of the soccer ball.
Robbers Cave
Clipper Circuit
The operation of a clipper circuit can be exemplified by analyzing a dual-clipper configuration setup that integrates two ideal diodes, each paired with a biasing...
Competition
Hydraulic Jump
Turbine-Governor Control

