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Effects of astaxanthin on human blood rheology

Hiromi Miyawaki1, Jiro Takahashi, Hiroki Tsukahara

  • 1Miyawaki Orthopedic Clinic, Hokkaido 061-1431, Japan.

Journal of Clinical Biochemistry and Nutrition
|September 27, 2008
PubMed

Effects of astaxanthin (AX) derived from H. pluvialis on human blood rheology were investigated in 20 adult men with a single-blind method. The experimental group was 57.5 +/- 9.8 years of age and the placebo group was 50.8 +/- 13.1 years of age. A blood rheology test that measures whole blood transit time was conducted using heparinized blood of the volunteers by a MC-FAN apparatus (microchannel array flow analyzer). After administration of AX 6 mg/day for 10 days, the values of the experimental group were decreased from 52.8 +/- 4.9 s to 47.6 +/- 4.2 s (p<0.01) and a comparison of the values between the experimental (47.6 +/- 4.2 s) and the placebo (54.2 +/- 6.7 s) groups showed a significant difference (p<0.05). There were no adverse effects resulting from the administration of AX 6 mg/day for 10 days. Informed consent was obtained from each subject.

Keywords:
astaxanthinblood rheologyblood transit timemale volunteersmicrochannel array flow analyzer

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