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Related Concept Videos

Molecular Models02:00

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Two-Dimensional (2D) NMR: Overview01:12

Two-Dimensional (2D) NMR: Overview

The 1D NMR spectrum of large and complex molecules like natural products has complicated splitting patterns and overlapping signals, which can be easily interpreted using 2-dimensional (2D) NMR. Unlike 1D NMR, 2D NMR has two frequency axes that provide the coupling information between the nucleus A and nucleus B in a molecule. The process from which 2D spectra are obtained has four steps.
The first step is the preparation period, during which nucleus A is excited with a radiofrequency pulse.
Network Covalent Solids02:18

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...

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Related Experiment Video

Updated: Jun 30, 2026

Neurovascular Network Explorer 2.0: A Simple Tool for Exploring and Sharing a Database of Optogenetically-evoked Vasomotion in Mouse Cortex In Vivo
08:32

Neurovascular Network Explorer 2.0: A Simple Tool for Exploring and Sharing a Database of Optogenetically-evoked Vasomotion in Mouse Cortex In Vivo

Published on: May 4, 2018

Browsing multidimensional molecular networks with the generic network browser (N-Browse).

Huey-Ling Kao1, Kristin C Gunsalus1

  • 1New York University, New York, New York.

Current Protocols in Bioinformatics
|September 27, 2008
PubMed
Summary

N-Browse offers dynamic visualization of molecular interaction networks. This Java applet provides interactive access to complex biological data, adaptable for any domain.

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Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
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Neurovascular Network Explorer 2.0: A Simple Tool for Exploring and Sharing a Database of Optogenetically-evoked Vasomotion in Mouse Cortex In Vivo
08:32

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Visualization

Background:

  • Molecular interaction data is complex and requires effective visualization tools.
  • Existing methods may lack interactivity or the ability to handle heterogeneous data sources.

Purpose of the Study:

  • To introduce N-Browse, a graphical network browser for visualizing and navigating molecular interaction data.
  • To provide dynamic, interactive, on-demand access to network data.

Main Methods:

  • Developed N-Browse as a Java applet for web browser integration.
  • Implemented a client-server architecture for remote data access.
  • Designed a generic database schema for adaptability.

Main Results:

  • N-Browse enables easy-to-use, simultaneous exploration of multiple functional information layers.
  • The tool facilitates dynamic and interactive visualization of heterogeneous molecular interaction networks.
  • The generic schema allows adaptation to various knowledge domains beyond biology.

Conclusions:

  • N-Browse provides a powerful and flexible solution for visualizing complex network data.
  • The freely available client-server package supports data producers in distributing interactive visualizations.
  • N-Browse enhances the exploration and understanding of interconnected data.