Cortical spreading edema in persistent visual migraine aura
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Updated: Jun 30, 2026

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Published on: June 2, 2014
Dániel Bereczki1, József Kollár, Norbert Kozák
1Semmelweis University, Department of Neurology, Budapest, Balassa, U. L, H-1083, Hungary.
Abstract:
We present imaging evidence of the spreading of cortical edema with reversibly restricted water diffusion from the left occipital to the temporoparietal cortex in persistent visual migraine aura in a 58-year-old man. The right-sided visual field defect lasting for 15 days was associated with discoupling of glucose metabolism and blood flow and the decreased apparent diffusion coefficient also suggested cytotoxic edema. At 8 weeks no signs were present, and magnetic resonance imaging became normal; therefore, long-lasting restricted cortical water diffusion, even if coupled with hypometabolism and edema, can be reversible in persistent visual migraine aura.
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