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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
A case of lymphangioleiomyomatosis with membranous nephropathy and likely systemic lupus
Ramin Sam1,2, Samra Khalid3, Carolyn Brecklin4,5
1Division of Nephrology, San Francisco General Hospital, 1001 Potrero Ave, Building 100, Rm 349, San Francisco, CA, 94110-1341, USA. samr@medsfgh.ucsf.edu.
Abstract:
Membranous glomerulonephritis is most often idiopathic, but it can be secondary to systemic lupus erythematosus, viral hepatitis, and drugs. A number of malignancies have also been associated with membranous glomerulonephritis, although a causal link has not been established yet. A young patient with lymphangioleiomyomatosis is described who developed massive proteinuria and was found to have membranous glomerulonephritis on renal biopsy. There were many pathological features and some clinical features that suggested the patient also suffered from systemic lupus erythematosus.
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