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Updated: Jun 30, 2026
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Efficacy of computer aided analysis in detection of significant coronary artery stenosis in cardiac using dual source
Anja J Reimann1, Ilias Tsiflikas, Harald Brodoefel
1Department of Diagnostic Imaging and Intervention, Diagnostic Radiology, University of Tuebingen, Hoppe Seyler Strasse 3, 72074 Tuebingen, Germany. anja.reimann@med.uni-tuebingen.de
Objective:
To analyze the diagnostic efficacy of computer aided analysis of relevant coronary artery stenosis using dual source computed tomography (DSCT).
Methods:
In a larger scale study patients scheduled for conventional coronary angiography (CA) were additionally examined with DSCT. Based on a 13-segment model 30 CT scans of this study population were analyzed for significant stenosis using conventional 3D charts (3D) as well as a specialized cardiac analysis tool (CAT). Diagnostic accuracy and time to diagnosis was recorded for each vessel separately as well as the three readers' confidence.
Results:
With severe coronary artery calcifications, 53 false interpretations of segments were found for the total of 390 coronary segments analyzed. 3D and CAT analysis showed a Sensitivity, Specificity, PPV and NPV of 0.59, 0.91, 0.57, 0.92 and 0.57, 0.92, 0.56, 0.92, respectively. No significant differences in diagnostic accuracy could be found between 3D and CAT (P = 0.1667). 3D took a mean of 5.2 min (3-10 min). With CAT a mean time of 8.2 min (4-12 min) was needed. No significant inter-reader time differences (P = 0.4954) and no significant confidence level differences were found between readers and analyzes.
Conclusion:
CAT of the coronary tree shows comparable accuracy to manual 3D analysis but needs improvements concerning coronary tree segmentation times.
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