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Updated: Jan 10, 2026

Assessing Energy Substrate Oxidation In Vitro with 14CO2 Trapping
Published on: March 23, 2022
Climacteric, physically active women ingesting their routine diet oxidize more carbohydrates than lipids
R D S Santos1, V M M Suen, O Iannetta
1Department of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, FMRP-USP, Brazil.
Objective:
To investigate the influence of a routine Brazilian diet on the rate of oxidation of energy substrates in climacteric, obese women, who came to the outpatient clinic of the Hospital of the School of Medicine of Ribeirao Preto (HCFMRP-USP).
Methods:
Subjects were recruited from outpatients at the Climacteric Clinic of the HCFMRP-USP, who were aged between 39 and 65 years and who voluntarily agreed to participate in this study. They were submitted to anthropometric measurements and indirect calorimetry for resting energy expenditure and substrate oxidation rate determination.
Results:
The carbohydrate oxidation in the group of climacteric, obese women showed a significant positive correlation between energy consumption at rest and ingestion of carbohydrates (in grams); the subjects' rate of lipid intake showed a significant negative correlation with their body mass index, waist circumference, and daily total caloric intake.
Conclusion:
Carbohydrate intake and carbohydrate oxidation rate may contribute to weight gain in climacteric women.
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