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Predictors of rate of weight gain in malnourished children within a realimentation programme
John D McLennan1, Rosanne M T Mills, Gordon H Fick
1Faculty of Medicine, University of Calgary, Calgary, Canada. jmclenna@ucalgary.ca
Insights
Caloric intake significantly impacts weight gain in malnourished children during realimentation programs. This effect is more pronounced in children with severe wasting and diarrhea, highlighting key factors for nutritional recovery.
Area of Science:
- Pediatrics
- Nutrition Science
- Public Health
Background:
- Malnourished children in realimentation programs exhibit significant variability in weight gain rates.
- Predictors for this weight gain variation are seldom reported, necessitating further investigation.
Purpose of the Study:
- To identify predictors of weight gain rate in children undergoing nutritional rehabilitation.
- To assess the impact of caloric intake on weight gain in a specific treatment program.
Main Methods:
- A cohort of 105 children admitted to a partial day treatment program in the Dominican Republic was studied.
- Weight gain rate was analyzed in relation to caloric intake, initial weight, and presence of diarrhea over the first 28 days.
Main Results:
- The mean weight gain rate was 3.8 g/kg/day.
- Caloric intake from formula was positively associated with weight gain.
- This association was stronger in children with higher degrees of wasting and more diarrhea.
Conclusions:
- Caloric intake is a significant predictor of weight gain in malnourished children.
- The impact of caloric intake is modulated by the severity of wasting and diarrhea.
- Further research is needed to identify additional predictors and improve nutrition treatment programs.
Abstract:
The rate of weight gain of malnourished children in realimentation programmes varies substantially; however, predictors of variation are infrequently reported. The aim of this study was to assess a set of hypothesized predictors to the rate of weight gain of a sample of children attending a partial day treatment programme in the Dominican Republic. Data were available for 105 consecutive admissions (82% of total) to the programme between July 2004 and June 2006. Mean rate of weight gain, adjusted for initial weight, was 3.8 (SD 4.2) g kg(-1) day(-1) during the first 28 days of treatment. Rate of weight gain was associated with the amount of calories consumed by the child from the enriched milk-based formula consumed within the clinic. This relationship depended upon the initial degree of wasting and the amount of diarrhoea, such that caloric intake had a greater impact on those with the most wasting and greater amounts of diarrhoea. Other hypothesized variables were not related to rate of weight gain. Further investigation is required to identify other predictors of the variability in weight gain within nutrition treatment programmes with tighter control of possible sources of measurement error.
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