Related Experiment Video
Updated: Jun 30, 2026

Studies on the Anti-Inflammatory Effect of Xiaoyao Pills in The Treatment of Postmenopausal Osteoporosis in Mice
Published on: August 23, 2024
Effects of 5-Form, Yang Style Tai Chi on older females who have or are at risk for developing osteoporosis
1Research and Development, John P. Murtha Neuroscience and Pain Institute, Johnstown, PA 15904, USA. lmurphy@conemaugh.org
Abstract:
This study investigated the effects of 5-Form, Yang Style Tai Chi (TC) on balance confidence, balance performance, functional strength, mobility, and incidence of falls among individuals with or at risk for developing osteoporosis. This was a pilot outcomes study in which participants served as their own controls. Thirty-one independent, community-dwelling women (mean age of 67.3 years) attended TC sessions twice a week for 12 weeks and practiced at least 1 day a week on their own. A specific TC instruction video was used to facilitate home practice. Baseline, immediate postintervention, and 6 and 12 months postintervention data were recorded. Outcome measures included the Activities-specific Balance Confidence (ABC) Scale, One-Legged Stance Test (OLST) for both legs, Repeated Chair Stands (RCS), and the Timed Up and Go Test (TUG). Exercise performance and falls were tracked during the study by using daily diaries. Balance performance, functional strength, and mobility significantly improved (p < 0.05) immediately postintervention. Most benefits were sustained at 6 months, but only functional strength and mobility remained improved at 12 months postintervention. Most participants reported exercising at the 6- and 12-month follow-up. However, very few individuals continued to practice TC on a regular basis (more than once a week) beyond the 12-week intervention. Balance confidence or incidence of falls did not improve.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
The Effect of Aging on Tissues
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Osteoclasts in Bone Remodeling