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Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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22q11 deletion syndrome: is that what they used to call . . . ?

Mary Grace Umlauf1

  • 1Capstone College of Nursing, University of Alabama, Tuscaloosa, AL, USA. mgumlauf@bama.ua.edu

Perspectives in Psychiatric Care
|October 2, 2008
PubMed
Abstract

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During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
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