Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Academic Value Units in Emergency Medicine: Current State and a Framework for Recognizing and Sustaining Academic Contributions.

AEM education and training·2026
Same author

Artificial intelligence in emergency medicine: a narrative review.

The American journal of emergency medicine·2026
Same author

From Roadmap to Reality: Securing the Future of Emergency Medicine Research.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2025
Same author

Horizontal Violence Toward Emergency Medicine Residents: Gender as a Risk Factor.

The western journal of emergency medicine·2022
Same author

Dynamic Masking: A Proposal of Burden-Based Metrics for Masking in K-12 Schools During the COVID-19 Pandemic.

The Journal of school health·2021
Same author

COVID-19 Transmission during Transportation of 1st to 12th Grade Students: Experience of an Independent School in Virginia.

The Journal of school health·2021

Related Experiment Video

Updated: Jun 29, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

Pediatric myth: fever and petechiae.

Martin D Klinkhammer1, James E Colletti

  • 1Department of Emergency Medicine, Regions Hospital, Saint Paul, Minnesota, USA.

CJEM
|October 2, 2008
PubMed
Summary

Children with fever and petechiae may not always have bacterial sepsis. Differentiating meningococcal disease is key for appropriate treatment and hospital admission decisions.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Petechiae and fever in children often prompt concern for bacterial sepsis, such as meningococcemia.
  • This can lead to automatic antibiotic administration, blood cultures, cerebrospinal fluid analysis, and hospital admission.

Purpose of the Study:

  • To review the literature and challenge the assumption that all children with petechiae and fever require immediate sepsis treatment.
  • To provide guidance on differentiating meningococcal disease and guiding appropriate management strategies.

Main Methods:

  • Literature review of studies on pediatric petechial rashes and fever.
  • Analysis of clinical signs and symptoms associated with meningococcal disease versus other conditions.
  • Evaluation of C-reactive protein (CRP) levels as a diagnostic marker.

Related Experiment Videos

Last Updated: Jun 29, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

Main Results:

  • Children with purpura/petechiae, ill appearance, and signs of shock (delayed capillary refill, hypotension) require prompt treatment for meningococcal disease.
  • Petechial rash limited to the superior vena cava distribution suggests a lower likelihood of meningococcal disease, potentially allowing outpatient management.
  • Normal CRP levels (<6 mg/L) in children with petechiae and fever, after initial antibiotic and blood culture, may allow for safe discharge with follow-up.
  • Elevated CRP levels (>6 mg/L) indicate a higher likelihood of serious infection, warranting hospital admission.

Conclusions:

  • Clinical presentation and rash distribution are crucial in assessing children with petechiae and fever.
  • C-reactive protein levels can aid in decision-making for hospital admission versus outpatient management.
  • A nuanced approach, rather than automatic sepsis treatment, is appropriate for children presenting with petechiae and fever.