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Fracture healing of chick femurs in tissue culture
K Takahashi1, M D Shanahan, L A Coulton
1Department of Orthopedics, Nagasaki University School of Medicine, Japan.
Acta Orthopaedica Scandinavica
|August 1, 1991
Abstract:
Embryonic chick femurs were isolated, and a transverse osteotomy was performed at the midshaft. The femurs were transplanted individually onto the host chorioallantoic membrane and incubation continued. Cultured femurs were harvested at intervals from 1 to 9 days after the transplant. Histologic examinations showed that repair progressed rapidly: the fracture gap was invaded by blood vessels and fibrous ingrowth. Ossification followed, and the repair process was completed by Day 9.