Related Experiment Video
Updated: Jun 29, 2026

10:27
Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
Molecular surveillance for multidrug-resistant Plasmodium falciparum, Cambodia
Naman K Shah1, Alisa P Alker, Rithy Sem
1University of North Carolina School of Public Health, Chapel Hill, North Carolina, USA.
Emerging Infectious Diseases
|October 2, 2008
Abstract:
We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004-2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate-mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.

