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Updated: Jun 29, 2026

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OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
Blood loss during transvaginal oocyte retrieval
Guido Ragni1, Claudia Scarduelli, Graziella Calanna
1Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
Gynecologic and Obstetric Investigation
|October 2, 2008
Summary
Transvaginal oocyte retrieval typically results in minimal blood loss. This study found that blood loss and related indicators were clinically insignificant in most women undergoing the procedure.
Area of Science:
- Reproductive Medicine
- Gynecologic Surgery
- Assisted Reproductive Technologies
Background:
- Quantifying blood loss during transvaginal oocyte retrieval is crucial for patient safety.
- Limited data exists on blood loss associated with uncomplicated procedures.
Purpose of the Study:
- To evaluate the quantity of blood loss following transvaginal oocyte retrieval.
- To assess changes in hematologic parameters and pelvic fluid post-procedure.
Main Methods:
- 150 women undergoing oocyte retrieval were assessed.
- Blood tests and transvaginal ultrasounds were performed pre-retrieval, 4-6 hours post-retrieval, and 72 hours post-retrieval.
Main Results:
- A median blood loss of 72 ml was estimated.
- No women experienced significant hemoglobin reduction (>2 g/day), pelvic fluid increase (>200 ml), or blood loss (>500 ml).
- Hematologic parameters and pelvic fluid showed no significant worsening at 72 hours.
Conclusions:
- Blood loss after transvaginal oocyte retrieval is generally clinically unremarkable.
- The procedure is associated with minimal complications related to blood loss.
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