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Updated: Jun 29, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
Digital vasculitis: a late complication of anti-tumour necrosis factor alpha therapy
Pamela Mangat1, Samuel Whittle, Les Cleland
1Rheumatology Department, Royal Adelaide Hospital, North Terrace, Adelaide, Australia. pm897@hotmail.com
Abstract:
Anti-tumour necrosis factor alpha therapy has led to significant advancement in the treatment of rheumatological disease. Rarely, anti-TNFalpha antagonists have been associated with vasculitis, predominantly cutaneous leukocytoclastic vasculitis. We present the first case of angiographically-confirmed digital vasculitis occurring as a late complication of etanercept therapy. Our case adds to the limited repertoire of case reports of anti-TNFalpha induced vasculitis and highlights the potential risk of this serious complication occurring up to several years after initiation of these agents.
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