Related Experiment Videos
Ocular infections associated with Comamonas acidovorans
K G Stonecipher1, H G Jensen, P R Kastl
1Department of Ophthalmology, Dean A. McGee Eye Institute, Oklahoma City, Oklahoma 73104.
Abstract:
Comamonas acidovorans (Pseudomonas acidovorans) is a ubiquitous gram-negative rod. Although generally considered nonpathogenic, we found C. acidovorans to be associated with six cases of ocular infections. The organism was the only isolate in three cases, whereas an association of other organisms was present in three cases. The multiple resistance patterns of these strains to antibiotic susceptibility testing emphasizes the need for culturing ocular infections. We recommend the identification and susceptibility testing of all ocular gram-negative rod isolates.
Insights
Comamonas acidovorans, a common bacterium, was linked to six eye infections. This highlights the importance of culturing and testing all gram-negative bacteria from eye infections for antibiotic resistance.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Comamonas acidovorans (formerly Pseudomonas acidovorans) is a Gram-negative bacterium commonly found in various environments.
- While typically considered nonpathogenic, its role in human infections requires further investigation.
Observation:
- This study identified Comamonas acidovorans in six cases of ocular infections.
- In three of these cases, C. acidovorans was the sole causative agent.
- The remaining three cases involved C. acidovorans in conjunction with other microorganisms.
Findings:
- The isolated strains of C. acidovorans exhibited multiple antibiotic resistance patterns.
- Antibiotic susceptibility testing revealed significant resistance, underscoring treatment challenges.
Implications:
- The findings emphasize the critical need for routine culturing of ocular infections to identify causative agents.
- Accurate identification and antibiotic susceptibility testing of all ocular Gram-negative rod isolates are recommended for effective patient management.