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Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study
S R Machlin1, G J Harris, G D Pearlson
1Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, MD.
The American Journal of Psychiatry
|September 1, 1991
Abstract:
Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.