Related Experiment Videos
Effects of fluoxetine on regional cerebral blood flow in obsessive-compulsive patients
R Hoehn-Saric1, G D Pearlson, G J Harris
1Department of Psychiatry, Johns Hopkins Hospital, Baltimore, MD 21205.
The American Journal of Psychiatry
|September 1, 1991
Abstract:
Six drug-free obsessive-compulsive patients were given single photon emission computerized tomography scans before and during treatment with fluoxetine. The treatment significantly reduced the patients' "hyperfrontality," as determined by the ratio between medial-frontal and whole cerebral cortex blood flow, and significantly lowered ratings of obsessive-compulsive and anxiety symptoms.