Related Experiment Video
Updated: Jun 29, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
Intraoperative coronary graft assessment
1Heart Hospital Baylor Plano, Dallas, Texas 75230, USA. mmack@csant.com
Insights
Early graft failure after coronary artery bypass grafting is common. Simple intraoperative methods like transit time flow measurement and fluorescence imaging can predict graft failure, potentially reducing occlusion rates.
Area of Science:
- Cardiovascular Surgery
- Medical Imaging
- Surgical Technology
Background:
- Coronary artery bypass grafting (CABG) is a common procedure for treating coronary artery disease.
- Graft failure, including early occlusion, remains a significant complication, impacting long-term patient outcomes.
- Current intraoperative graft assessment practices are infrequent, leading to missed opportunities for early intervention.
Purpose of the Study:
- To review the incidence and impact of early graft occlusion following CABG.
- To evaluate the effectiveness of available intraoperative graft assessment techniques.
- To highlight the potential of underutilized methods in improving CABG success rates.
Main Methods:
- Review of existing literature on intraoperative graft assessment in CABG.
- Analysis of reported graft closure rates and detection capabilities of various methods.
- Comparison of traditional methods (coronary angiography) with newer techniques (transit time flow measurement, intraoperative fluorescence imaging).
Main Results:
- Immediate graft closure rates range from 5-9%, with 1-year closure rates reaching 20-30%.
- Coronary angiography, while accurate, faces logistical and image quality challenges, limiting its intraoperative use.
- Transit time flow measurement and intraoperative fluorescence imaging demonstrate high safety, simplicity, and expeditiousness, with reported graft failure detection rates of 2-5%.
Conclusions:
- Early graft occlusion is a frequent and significant problem after CABG.
- Transit time flow measurement and intraoperative fluorescence imaging are reliable, underutilized tools for predicting graft failure.
- Increased adoption of these techniques and the availability of hybrid operating rooms for intraoperative angiography could substantially reduce graft failure rates.
Purpose Of Review:
Intraoperative graft assessment in coronary artery bypass grafting is infrequently performed. Nevertheless, studies show an immediate graft closure rate of 5-9% and a 1-year closure rate of 20-30%.
Recent Findings:
Coronary angiography is the 'gold standard' for graft assessment yet has been seldom employed because of logistical problems and image quality. Two methods, transit time flow measurement and intraoperative fluorescence imaging are simple, safe, and expeditious. Intraoperative graft failure detection rates of 2-5% have been reported.
Summary:
Early graft occlusion occurs frequently after coronary artery bypass grafting. Two relatively simple but underutilized methods of intraoperative graft assessment have been shown to be predictive of graft failure. Wider use of these techniques as well as wider availability of hybrid operating rooms, which will allow intraoperative coronary angiography, may reduce graft failure.
More Related Videos
05:25Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018