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Related Experiment Video

Updated: Jun 29, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Malignant mental nerve neuropathy: systematic review.

Sónnica Galán Gil¹, Maria Peñarrocha Diago, Miguel Peñarrocha Diago

¹Valencia University Medical and Dental School, Spain.

Medicina Oral, Patologia Oral Y Cirugia Bucal

|October 3, 2008

Summary

Malignant mental neuropathy (MMN), a cancer-related nerve issue, often signals advanced disease. Early MMN detection can indicate recurrence, highlighting the need for prompt cancer evaluation.

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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

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Published on: April 26, 2012

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Published on: May 17, 2024

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Published on: April 26, 2012

Area of Science:

Neurology
Oncology
Radiology

Background:

Malignant mental neuropathy (MMN) is a neurological symptom of cancer affecting the mental nerve.
It presents as altered sensation in the lower lip and chin area.

Purpose of the Study:

To systematically review the literature on MMN.
Analyze its etiology, pathogeny, clinical features, diagnostic tests, and prognosis.

Main Methods:

Systematic literature review of 16 studies.
Analysis of 136 patient cases.
Review of diagnostic imaging like orthopantomographs and CT scans.

Main Results:

Breast cancer and lymphomas were common associated malignancies.
Mandibular lesions and skull base tumors were frequent causes.
MMN presented as a primary symptom in 27.7% and recurrence in 37.7% of cases.
The mandible was the most affected region.

Conclusions:

MMN indicates a poor prognosis for cancer patients.
High mortality (78.5%) was observed within months of MMN onset.