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Congenital diaphragmatic hernia in a developing country
1Department of Paediatrics, Kasturba Medical College, Manipal University, Udupi District, Karnataka 576104, India. docrameshbhat@yahoo.co.in
Singapore Medical Journal
|October 3, 2008
Summary
Congenital diaphragmatic hernia (CDH) outcomes in developing countries are poorly understood. This study found over 50% survival with conventional ventilation, but early symptoms indicate a poor prognosis for neonates with CDH.
Area of Science:
- Pediatric Surgery
- Neonatal Care
- Congenital Anomalies
Background:
- Congenital diaphragmatic hernia (CDH) presents a significant challenge in neonatal care, with outcomes varying widely.
- Limited data exists on CDH management and outcomes specifically from developing countries.
Purpose of the Study:
- To investigate the management and outcomes of neonates diagnosed with congenital diaphragmatic hernia (CDH).
- To identify prenatal and postnatal factors influencing the survival rates of neonates with CDH.
Main Methods:
- A retrospective review was conducted on neonates diagnosed with CDH and admitted to a teaching hospital.
- Data collected included demographics, prenatal/postnatal factors, birth details, management strategies, and patient outcomes, with survival as the primary endpoint.
Main Results:
- Out of 16 neonates with CDH, 56.3% survived. Left-sided hernias were observed in all cases.
- Prenatally detected CDH cases showed significantly lower survival rates and Apgar scores.
- Most deaths occurred within 72 hours, and symptomatic presentation within 12 hours was linked to poor outcomes.
Conclusions:
- A survival rate exceeding 50% was achieved for neonates with CDH using conventional ventilation methods.
- Neonates presenting with symptoms within the first 12 hours of life are at higher risk for poor outcomes.
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