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Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Sleeve gastrectomy leads to Helicobacter pylori eradication
Dean Keren1, Ibrahim Matter, Tova Rainis
1Gastroenterology Unit, Surgery Department, Bnai Zion Medical Center, Technion-Institute of Technology, Haifa, Israel. Dean.keren@b-zion.org.il
Obesity Surgery
|October 3, 2008
Summary
Helicobacter pylori (HP) infection is common in patients undergoing laparoscopic sleeve gastrectomy (LSG). Treating only symptomatic patients preoperatively resolved symptoms, suggesting LSG may aid HP eradication.
Area of Science:
- Gastroenterology
- Bariatric Surgery
- Microbiology
Background:
- The prevalence and impact of Helicobacter pylori (HP) in patients undergoing laparoscopic sleeve gastrectomy (LSG) remain unevaluated.
- HP infection is a significant factor in gastrointestinal health and disease.
Purpose of the Study:
- To investigate the role and prevalence of HP in patients before and after LSG.
- To assess the efficacy of HP eradication therapy in symptomatic patients undergoing LSG.
Main Methods:
- A 24-month study included obese patients undergoing LSG.
- Presurgical HP breath tests were conducted; symptomatic patients received triple therapy.
- Excluded stomachs were evaluated for HP post-surgery, with follow-up 13C-urea breath tests (UBT) for positive cases.
Main Results:
- Of 40 patients, 15 (37.5%) had presurgical HP; 11 symptomatic patients receiving therapy showed complete symptom resolution.
- HP was detected in 17 of 40 excluded stomachs (42.5%).
- Three months post-surgery, only three patients (17.6%) tested positive on 13C-UBT.
Conclusions:
- HP infection is frequent in patients undergoing LSG, but most follow-up tests were negative.
- Routine screening and treatment for all HP-positive LSG patients may be unnecessary.
- LSG might contribute to HP eradication, warranting further investigation into clinical implications.
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