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Nodular fasciitis in the submandibular gland
Eun Jeong Jang1, Tae In Park, Sang Chul Nam
1Department of Pathology, Kyungpook National Univerisity Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
Diagnostic Cytopathology
|October 3, 2008
Summary
Nodular fasciitis (NF), a benign myofibroblast proliferation, rarely occurs in adult submandibular regions. This case highlights a rapidly growing submandibular mass diagnosed as NF.
Area of Science:
- Pathology
- Oncology
Background:
- Nodular fasciitis (NF) is a benign myofibroblast proliferation, typically affecting extremities and trunk.
- Head and neck NF is less common, but it is the most frequent site in pediatric populations.
- NF in the adult submandibular region is exceptionally rare.
Observation:
- A 53-year-old male presented with a rapidly growing submandibular mass over 10 days.
- Cytology revealed uniform spindle cells without atypia or mitosis, and focal loose stroma.
- The mass was located adjacent to the parotid gland.
Findings:
- Histologic and immunohistochemical analysis confirmed nodular fasciitis in the submandibular region.
- The lesion demonstrated characteristic features of benign myofibroblastic proliferation.
- Differential diagnoses for spindle cell lesions in this location were considered.
Implications:
- This case expands the known clinical spectrum of nodular fasciitis presentation.
- Accurate diagnosis is crucial for appropriate management and avoiding unnecessary aggressive treatment.
- Understanding rare presentations aids in clinical recognition and diagnostic accuracy for head and neck masses.
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