Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypoxia01:23

Hypoxia

Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engaging Peer Mentors for Opportunity, Well-Being, and Equity Realization-A Leadership Intervention for Women in Academic Medicine.

Journal of women's health (2002)·2025
Same author

Wound Healing Society 2023 update on guidelines for arterial ulcers.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society·2024
Same author

"The Adjunct Faculty Are Our Lifeblood" An Institution's Response to Deliver Value to Volunteer Community Faculty.

Family medicine·2021
Same author

Representation of women plenary speakers at the American Academy of Neurology Annual Meeting.

Neurology·2020
Same author

Disruptive Behavior in Medicine: Sources, Impact, and Management.

Anesthesia and analgesia·2020
Same author

Recruitment of Women to Anesthesiology: Parallels to Surgery and Interventional Radiology.

Journal of surgical education·2020
Same journal

Reimagining cardiac surgery-the emerging role of prehabilitation and risk optimization.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Prehabilitation and enhanced recovery after cardiac surgery.

Best practice & research. Clinical anaesthesiology·2026
Same journal

The role of biomarkers in the preoperative evaluation of cardiac surgical patients - A narrative review.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Magic in a bottle? A Focused review of factor concentrates for the intraoperative treatment of acquired coagulopathy - Fibrinogen concentrate, prothrombin complex concentrate, and recombinant activated factor VII.

Best practice & research. Clinical anaesthesiology·2025
Same journal

ESAs in perioperative anemia management: Who, what, how and why?

Best practice & research. Clinical anaesthesiology·2025
Same journal

Does patient blood management represent good value for money?

Best practice & research. Clinical anaesthesiology·2025
See all related articles

Related Experiment Video

Updated: Jun 29, 2026

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

Hyperoxia and infection.

Harriet W Hopf1, James Holm

  • 1Department of Anesthesiology, University of Utah, Room 3C444, 30 N 1900 East, Salt Lake City, UT 84132, USA. harriet.hopf@hsc.utah.edu

Best Practice & Research. Clinical Anaesthesiology
|October 4, 2008
PubMed
Summary
This summary is machine-generated.

Optimizing perioperative oxygenation can significantly reduce surgical site infections. Increased inspired oxygen and hyperbaric oxygen therapy are effective strategies for preventing and treating wound infections.

More Related Videos

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

Related Experiment Videos

Last Updated: Jun 29, 2026

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

Area of Science:

  • Surgical site infection
  • Wound healing
  • Hyperoxia

Background:

  • Surgical wound infection is a common complication.
  • Patient factors, environmental stressors, and individual stress response impact wound outcomes.
  • Wounds are highly sensitive to hypoxia, a preventable condition.

Purpose of the Study:

  • To review the basic science and clinical data supporting hyperoxia in preventing and treating surgical infections.
  • To highlight the importance of perioperative management in promoting wound healing and infection resistance.

Main Methods:

  • Review of basic science principles related to oxygen and wound healing.
  • Analysis of clinical data on the efficacy of increased inspired oxygen and hyperbaric oxygen therapy.
  • Discussion of perioperative strategies to optimize wound oxygenation.

Main Results:

  • Maintaining adequate wound perfusion and oxygenation is critical for healing and infection resistance.
  • Increased inspired oxygen demonstrably reduces surgical site infections in at-risk patients.
  • Hyperbaric oxygen is a valuable adjunct for treating severe soft tissue and bone infections.

Conclusions:

  • Perioperative hyperoxia is a key factor in preventing and treating surgical wound infections.
  • Optimizing oxygen delivery to surgical wounds improves patient outcomes.
  • Further research and clinical application of hyperoxia strategies are warranted.