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Related Experiment Video

Updated: Jun 29, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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Published on: April 28, 2019

Acute hepatic failure due to dengue: A case report.

Subhash Giri1, Mukul P Agarwal, Vishal Sharma

  • 1Department of Medicine, University College of Medical Sciences, Delhi, India. docvishalsharma@gmail.com.

Cases Journal
|October 4, 2008
PubMed
Summary

Dengue, a widespread arboviral disease, can rarely cause acute hepatic failure. This case study details a young male patient who developed this severe liver complication from dengue, discussing diagnostic and treatment strategies.

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Area of Science:

  • Infectious Diseases
  • Hepatology
  • Virology

Background:

  • Dengue virus is a significant global arbovirus, prevalent in tropical and subtropical regions.
  • Hepatic involvement is a common manifestation of dengue infection.
  • Acute hepatic failure is a rare but severe complication of dengue fever.

Purpose of the Study:

  • To report a case of acute hepatic failure secondary to dengue infection in a young male.
  • To discuss the differential diagnoses for acute hepatic failure in the context of dengue.
  • To outline the management strategies for dengue-induced acute hepatic failure.

Main Methods:

  • Case report presentation.
  • Review of clinical presentation, laboratory findings, and diagnostic workup.
  • Discussion of differential diagnoses and treatment approaches.

Main Results:

  • A young male patient presented with symptoms consistent with acute hepatic failure.
  • Dengue virus infection was identified as the causative agent.
  • The patient's case highlights the rare but critical hepatic complication of dengue.

Conclusions:

  • Acute hepatic failure is an uncommon but serious complication of dengue infection.
  • Prompt recognition and appropriate management are crucial for patients with dengue-associated liver failure.
  • Further research into the mechanisms and optimal treatment of dengue-induced hepatic failure is warranted.