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Context dependent function of APPb enhancer identified using enhancer trap-containing BACs as transgenes in zebrafish

Leighcraft A Shakes1, Tennison L Malcolm, Kevin L Allen

  • 1Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Chemistry, North Carolina Central University, Durham, NC 27707, USA.

Nucleic Acids Research
|October 4, 2008
PubMed
Summary

Researchers identified a novel enhancer in the amyloid precursor protein gene (APPb) of zebrafish. This enhancer is crucial for specific neuronal expression, aiding Alzheimer

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