Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Walter Russell Brain (1895-1966).

Journal of neurology·2022
Same author

Pourfour du Petit (1664-1741).

Revue neurologique·2020
Same author

The "split brain" and Roger Wolcott Sperry (1913-1994).

Revue neurologique·2019
Same author

Early contribution of Alexandria medical school to the anatomy, physiology and pathology of the nervous system.

Revue neurologique·2018
Same author

Early Observations on Facial Palsy.

Journal of the history of the neurosciences·2014
Same author

Before Charcot.

Frontiers of neurology and neuroscience·2014
Same journal

Combined Olfactory Testing and Substantia Nigra Hyperechogenicity for Diagnostic Differentiation of Parkinson's Disease.

European neurology·2026
Same journal

The Role of Stroke Severity in the Association between Hypoperfusion Intensity Ratio and Futile Reperfusion after Endovascular Treatment.

European neurology·2026
Same journal

The Parkinsonism of Salvador Dalí.

European neurology·2026
Same journal

Disorders of Arousal and Sleep-Related Hypermotor Epilepsy in Adults: A Challenging but Necessary and Critical Distinctive Diagnosis.

European neurology·2026
Same journal

Sex-Specific Phenotypic Characteristics in Obstructive Sleep Apnea: A Comprehensive Analysis of Anthropometric, Hematological, and Metabolic Profiles Stratified by Disease Severity.

European neurology·2026
Same journal

Historical and Clinical Analysis of a Case of Progressive Muscular Atrophy (1853-1871).

European neurology·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection
05:55

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Mollaret's meningitis.

J M S Pearce1

  • 1Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary, Hull, UK.

European Neurology
|October 4, 2008
PubMed
Summary
This summary is machine-generated.

Pierre Mollaret described a benign, recurrent meningitis characterized by sterile inflammation and specific cell changes in cerebrospinal fluid. This condition, now termed Mollaret's meningitis, should be reserved for idiopathic recurrent aseptic meningitis.

More Related Videos

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Related Experiment Videos

Last Updated: Jun 29, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection
05:55

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pathology

Background:

  • Pierre Mollaret's contributions to infectious disease prevention are noted.
  • He described a unique syndrome of benign, recurrent meningitis in three patients.
  • This meningitis presented with recurrent fever, headache, vomiting, and sterile cerebrospinal fluid containing 'fantomes cellulaires' (cell ghosts).

Discussion:

  • The symptoms of Mollaret's meningitis are similar to those caused by Herpes simplex virus-2 and other viral infections.
  • The paper advocates for restricting the term Mollaret's meningitis to idiopathic recurrent aseptic meningitis.
  • This distinction is crucial for accurate diagnosis and understanding of recurrent meningitis etiologies.

Key Insights:

  • Mollaret's meningitis is defined by recurrent aseptic meningitis with characteristic cerebrospinal fluid findings.
  • The syndrome can be mimicked by viral infections, highlighting the importance of etiological differentiation.
  • The term's precise application is essential for clinical and research clarity.

Outlook:

  • Further research may elucidate the precise idiopathic causes of recurrent aseptic meningitis.
  • Understanding Mollaret's meningitis contributes to the broader field of neuroinflammatory disorders.
  • Differential diagnosis remains key in managing patients presenting with recurrent meningitis symptoms.