Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Pigmentation

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Mitral Valve Prolapse III: Nursing Management

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...

Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lost in translation: true clinical impact of reflectance confocal microscopy overlooked in 'Biopsy outperforms reflectance confocal microscopy in diagnosing and subtyping basal cell carcinoma: results and experiences from a randomized controlled multicentre trial'.

The British journal of dermatology·2020

Same author

Cell phone use in the clinic: "Please hang up now, the doctor is ready to see you!"

International journal of women's dermatology·2019

Same author

A deep look into thin melanomas: What's new for the clinician and the impact on the patient.

International journal of women's dermatology·2018

Same author

Skin cancer knowledge, attitudes, beliefs, and prevention practices among medical students: A systematic search and literature review.

International journal of women's dermatology·2018

Same author

A survey assessing the satisfaction of dermatology residents in the United States: How can we make dermatology residency training better?

International journal of women's dermatology·2018

Same author

Applying to dermatology residency: An ethical approach to an inherently unethical process.

International journal of women's dermatology·2018

Search research articles

Related Experiment Video

Updated: Jun 29, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Melanoma and pregnancy.

M S Driscoll¹, J M Grant-Kels

¹Department of Dermatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. bdriscollent@msn.com

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia

|October 4, 2008

Summary

Pregnancy does not worsen survival for women with localized cutaneous melanoma. Metastasis to the fetus is rare, and subsequent pregnancies or hormonal therapies do not appear to increase melanoma risk.

More Related Videos

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Related Experiment Videos

Last Updated: Jun 29, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Area of Science:

Oncology
Obstetrics & Gynecology
Dermatology

Background:

Melanoma during pregnancy presents complex challenges for both mother and fetus.
Previous reports suggested a poor prognosis, necessitating updated evidence-based guidance.

Purpose of the Study:

To analyze the impact of pregnancy on melanoma prognosis.
To assess fetal risk from maternal melanoma.
To provide counseling guidelines regarding future pregnancies and hormonal therapies.

Main Methods:

Review of recent controlled studies on melanoma survival in pregnant women.
Analysis of case reports and series on fetal and placental melanoma metastasis.
Evaluation of epidemiological data on hormonal therapies and melanoma risk.

Main Results:

Recent studies indicate pregnancy does not negatively affect survival for localized cutaneous melanoma.
Melanoma metastasis to the placenta is common, but fetal metastasis is rare.
Subsequent pregnancies and use of oral contraceptives or hormone replacement therapy do not appear to increase melanoma risk.

Conclusions:

Pregnancy does not alter the prognosis for women with localized cutaneous melanoma.
Fetal risk from maternal melanoma is minimal.
Women with a history of melanoma can be counseled regarding future pregnancies and hormonal therapies with low perceived risk.