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Updated: Jun 29, 2026

Meiotic Spindle Assessment in Mouse Oocytes by siRNA-mediated Silencing
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Meiotic Spindle Assessment in Mouse Oocytes by siRNA-mediated Silencing

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Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes

Stéphane Brunet1, Julien Dumont, Karen W Lee

  • 1UMR7622, Université Pierre et Marie Curie/CNRS, Bat. C, 5e, 9 quai Saint Bernard, Paris, France.

Plos One
|October 4, 2008
PubMed

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Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
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Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
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