Related Experiment Video
Updated: Jun 29, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Cephalometric superimposition on the occipital condyles as a longitudinal growth assessment reference: I-point and
Richard Standerwick1, Eugene Roberts, James Hartsfield
1Department of Orthodontics and Oral Facial Genetics, Indiana University, Indianapolis, Indiana 46202, USA. rjstanderwick@gmail.com
Abstract:
This retrospective study tests the hypothesis that superimposition referenced at the occipital condyles (defined as I-point, I-curve) and oriented to the anterior cranial base (ACB) will display a growth pattern that is more consistent with independent evaluations, such as the Melsen necropsy specimens and the Bjork implant studies, when compared with traditional superimpositions referenced at sella turcica. Twenty-eight sets of serial lateral cephalometric radiographs were selected from an archived growth study. The apparent facial growth was compared using polar coordinate analysis from superimposition tracings of the serial films for each subject. The two superimposition methods were compared. The traditional method, ACB registered on the anterior curvature of sella turcica, versus registration on I-point while maintaining ACB parallel. I-point registered superimpositions consistently displayed a facial growth pattern that was more consistent with the classic necropsy specimens of children and the cephalometric studies superimposing on implant markers. Traditional ACB superimposition suggests that airway is restricted by normal growth. This apparent physiologic artifact does not occur when superimpositions are registered on I-point. Sella turcica displays vertical movement that is consistent with brain growth. These data indicate that registration on I-point is a more accurate physiologic representation of facial growth than the traditional ACB superimpositions. When compared with the traditional registration at sella turcica, I-point superimposition better elucidates physiologic growth patterns. As cephalometrics evolve from a two to a three dimensional science, it is important to use a more biologically valid registration for evaluating therapeutics and facial growth patterns.
More Related Videos
Related Concept Videos
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Eccentric Axial Loading in a Plane of Symmetry

