Related Experiment Video

Updated: Jun 29, 2026

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
08:06

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

Published on: February 1, 2018

PASS-assisted exploration of antidepressant activity of 1,3,4-trisubstituted-beta-lactam derivatives

Munish Mittal1, Rajesh K Goel, Gaurav Bhargava

  • 1Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab 147002, India.

Bioorganic & Medicinal Chemistry Letters
|October 7, 2008
PubMed

Abstract:

Assisted by PASS predictions, the antidepressant activity of 1,3,4-trisubstituted monocyclic beta-lactams in seasonal affective disorders is described.

More Related Videos

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials
10:50

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials

Published on: April 10, 2016

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
08:23

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes

Published on: March 2, 2020

Related Experiment Videos

Last Updated: Jun 29, 2026

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
08:06

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

Published on: February 1, 2018

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials
10:50

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials

Published on: April 10, 2016

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
08:23

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes

Published on: March 2, 2020

Related Concept Videos

Inhibitors of Gram-positive Cell Wall Synthesis01:23

Inhibitors of Gram-positive Cell Wall Synthesis

Bacterial cell walls are typically rigid structures composed mainly of peptidoglycan, a mesh-like polymer that provides mechanical strength and maintains cell shape. The synthesis of peptidoglycan is a crucial process in bacterial growth and serves as a primary target for many antibiotics.Mechanism of Action of Beta-Lactam AntibioticsBeta-lactam antibiotics, such as penicillin, inhibit peptidoglycan synthesis in actively growing cells. These antibiotics share a characteristic four-membered...

Articles linked to this work by shared authors, journal, and citation graph.

Catalytic [6 + 3] cycloaddition for the synthesis of medium-sized ring systems: a critical review.

RSC advances·2026

Generation of a 3-Allyl/Propanylthiomethyl Ketene and their [4+2] Cycloadditions With 1,3-Diazabuta-1,3-dienes: Synthesis of 5-Allyl/propargyl-thio methyl Pyrimidinones.

Chemistry & biodiversity·2026

Design, Synthesis, and Anti-Inflammatory Activity of Functionalized 1,2,4,5-Tetrasubstituted-Pyrimidinone.

Chemistry & biodiversity·2026

Antidiabetic Evaluation of New Pyrimidine-Thiazoline Hybrids Endorsed With Enzyme Kinetic Studies and Computational Analysis.

Chemical biology & drug design·2025

Isoniazid-rhodanine molecular hybrids: design, synthesis, antimycobacterial activity and computational validation.

RSC advances·2025

DES-Promoted Synthesis of 3,4-Dihydropyrimidinones and Their Antidiabetic and Antioxidant Evaluation Supported With Computational Studies.

Chemistry & biodiversity·2025

Design, synthesis, and preliminary in vitro screening of novel tolmetin hydrazones against colon cancer.

Bioorganic & medicinal chemistry letters·2026

Discovery and characterization of potent and efficacious small-molecule parathyroid hormone Receptor-1 (PTH1R) antagonists for the treatment of hypercalcemia.

Bioorganic & medicinal chemistry letters·2026

Uncovering the importance of lipofection for aptamer-mediated therapeutic oligonucleotide delivery in a HER2+ SKBR3 breast cancer cell line.

Bioorganic & medicinal chemistry letters·2026

Synthesis and pharmacological evaluation of a series of fluoro-substituted 3-phenoxy-azetidines as cortical enhancers for the treatment of apathy.

Bioorganic & medicinal chemistry letters·2026

Discovery of potent GPR120 activators with fatty orosensation enhancement activity.

Bioorganic & medicinal chemistry letters·2026

Discovery of Fisetin as a potent and cell-active ACVR2A inhibitor.

Bioorganic & medicinal chemistry letters·2026

Acute psilocybin or ethocybin leads to a sustained increase in Pavlovian aversion memory in male mice.

Frontiers in pharmacology·2026

A review of multicomponent synthesis of Betti-base amidoalkyl naphthol (AAN) derivatives as substances of biological interest.

RSC advances·2026

Denatonium in Camellia japonica seeds: A synthetic bitterant found in nature.

Food chemistry: X·2026

Integrated Studies on the Biological Functions and Regulatory Mechanisms of Dedicator of Cytokinesis Family Proteins-Secondary Publication.

JMA journal·2026

Bioactive compounds from Tetradenia riparia and Tetracera poggei: antioxidant activity, UPLC-QTOF-MS phytochemical profiling, and in silico targeting of the RNA-binding protein DRBD18 of Trypanosoma brucei.

Frontiers in pharmacology·2026

Facile synthesis of trans racemic 1,4-diaryl substituted, proline esters via Ugi multicomponent reaction.

RSC advances·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us