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Updated: Jun 29, 2026
09:15
Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
Published on: May 7, 2019
Simultaneous heart and kidney transplantation from a single donor
Ron-Bin Hsu1, Meng-Kun Tsai, Po-Huang Lee
1Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan, ROC. ronbin@ntuh.gov.tw
Summary
Simultaneous heart and kidney transplants are viable for patients with end-stage heart and renal failure. However, outcomes were poor for UNOS status IA patients with prior cardiac surgery.
Area of Science:
- Cardiology
- Nephrology
- Transplantation Medicine
Background:
- Simultaneous heart and kidney transplantation (SHKT) lacks established guidelines for indications and contraindications.
- Co-existing end-stage heart and renal failure presents complex management challenges.
Purpose of the Study:
- To report the single-institutional experience with SHKT.
- To evaluate outcomes and identify factors influencing survival after SHKT.
Main Methods:
- Retrospective chart review of 13 patients undergoing SHKT between 1995 and 2006.
- Analysis of patient demographics, etiologies of heart and renal failure, UNOS status, and outcomes.
Main Results:
- Thirty-day mortality was 15% and in-hospital mortality was 38%.
- Patients in UNOS status II had better survival (80% at 1 year) than UNOS status IA (38% at 1 year).
- UNOS status IA patients frequently had prior cardiac surgery, rejection, and renal allograft complications.
Conclusions:
- SHKT is a viable option for select patients with combined heart and kidney failure.
- Clinical outcomes were unsatisfactory in UNOS status IA patients, particularly those with prior cardiac surgery.
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01:28Kidney Transplant I: Introduction
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01:26Kidney Transplant II: Surgical Procedure
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