Isolated extra-medullary relapse of acute leukemia following allogeneic bone marrow transplantation

Al Sabty Firas1, E Demeckova, E Bojtarova

  • 1Department of Hematology and Transfusion Medicine, Faculty of Medicine, University Hospital, Comenius University, Bratislava, Slovakia. firasalsabty@yahoo.com

Isolated extramedullary relapse (IEMR) of acute leukemia (AL) after allogeneic bone marrow transplantation (BMT) is a rare occurrence. It is seen more commonly after BMT than after conventional chemotherapy (CHT) alone. We describe the natural history and response to treatment in four patients with IEMR following allogeneic BMT. The results indicate a stronger graft-versus-leukemia (GVL) effect in the marrow than in the peripheral tissues (Fig. 4, Ref. 13). Full Text (Free, PDF) www.bmj.sk.