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Vancomycin-resistant enterococcus in pediatric oncology patients: An analysis of potential consequences of
Amanda Kosack1, Elyn Riedel, Timothy E Kiehn
1Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Abstract:
A retrospective analysis of 57 pediatric oncology patients with a baseline positive vancomycin-resistant enterococcus (VRE) culture who subsequently received chemotherapy and/or radiation therapy was performed. The incidence of subsequent VRE infection was calculated using a competing risk analysis accounting for death from non-VRE causes as a competing risk. Ten patients had subsequent VRE infection. The cumulative incidence of subsequent infection was 14% (7-27%, 95% confidence interval) at 1 year and 16% (9-29%, 95% confidence interval) at 2 years. None of the hypothesized risk factors appeared to differ between patients who developed a subsequent infection and those who did not.
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