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Related Experiment Video

Updated: Jun 29, 2026

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Published on: December 8, 2015

Micro/nanostructural porous surface on titanium and bioactivity.

Ling Gao¹, Bo Feng¹, Jianxin Wang¹

¹Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People's Republic of China.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials

|October 8, 2008

Summary

A novel micro/nanostructural porous titanium surface with anatase crystals enhances implant bioactivity. This surface promotes faster hydroxyapatite formation and protein adsorption for improved implant fixation.

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Last Updated: Jun 29, 2026

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Plasma Polishing as a New Polishing Option to Reduce the Surface Roughness of Porous Titanium Alloy for 3D Printing

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Area of Science:

Biomaterials Science
Surface Engineering
Orthopedic Implants

Background:

Porous implant surfaces promote better osseointegration compared to smooth surfaces.
Titanium's biocompatibility makes it a common implant material, but surface modification can enhance its performance.
Bioactivity, crucial for implant success, involves interactions with biological fluids and proteins.

Purpose of the Study:

To create and characterize a micro/nanostructural porous titanium surface.
To evaluate the bioactivity of the modified surface in simulated body fluid and protein solutions.
To determine if the surface modification enhances hydroxyapatite formation and protein adsorption.

Main Methods:

Microporous titanium surfaces were created using acid etching.
A micro/nanostructural porous layer was fabricated via acid etching and anodization.
Heat treatment converted surface oxides to anatase crystals.
Bioactivity was assessed using simulated body fluid and bovine serum albumin (BSA) solutions.
Surface characterization employed scanning electron microscopy, X-ray diffraction, and FTIR spectroscopy.

Main Results:

The micro/nanostructural porous surface with anatase exhibited excellent bioactivity without pretreatment.
Enhanced hydroxyapatite (HA) formation and faster BSA adsorption were observed compared to control samples.
The HA coating demonstrated greater thickness, absence of microcracks, and a strong substrate interface.

Conclusions:

The developed micro/nanostructural porous titanium surface with anatase shows significant potential for enhancing implant bioactivity.
This surface modification may serve as an ideal layer for fabricating advanced bioactive implants.
The improved HA formation and protein adsorption contribute to better early fixation and long-term stabilization.