Related Experiment Video
Updated: Jun 29, 2026
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Single left ventricle and pheochromocytoma
Yat W Cheung1, Daniel M Spevack
1Department of Medicine, Division of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine, Bronx, NY 10467, USA.
Congenital Heart Disease
|October 8, 2008
Summary
A rare congenital heart defect, Holmes heart, was diagnosed in a patient who later developed pheochromocytoma. This co-occurrence, seen in only a few cases, suggests a potential link between these conditions.
Area of Science:
- Cardiology
- Endocrinology
- Genetics
Background:
- Holmes heart is a rare congenital cardiac anomaly.
- Pheochromocytoma is a neuroendocrine tumor arising from the adrenal medulla.
Observation:
- A patient presented with a diagnosed Holmes heart from birth.
- The same patient was later diagnosed with pheochromocytoma during adolescence.
Findings:
- Literature review identified only two previously reported cases with both Holmes heart and pheochromocytoma.
- The simultaneous occurrence of these rare conditions in multiple individuals suggests a potential underlying association.
Implications:
- Further research is warranted to explore the potential genetic or developmental pathways linking Holmes heart and pheochromocytoma.
- This association may inform diagnostic approaches and risk stratification for patients with either condition.
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