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Updated: Jun 29, 2026
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Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors
Published on: December 3, 2013
Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems.
Alejandro Brun1, Emmanuel Albina, Tom Barret
1Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, 28130 Madrid, Spain. brun@inia.es
Vaccine
|October 8, 2008
Summary
Novel viral-vector based antigen delivery systems (ADSs) offer new vaccine strategies for animal viral diseases. These tools also advance research into species-specific immune responses and protection.
Area of Science:
- Veterinary Vaccinology
- Molecular Genetics
- Immunology
Background:
- Advances in molecular genetics, pathogenesis, and immunology enable rational vaccine design.
- Viral epizootic diseases pose significant threats to veterinary species.
Purpose of the Study:
- To review viral-vector based antigen delivery systems (ADSs) for veterinary vaccines.
- To highlight the utility of ADSs in understanding protective immune responses.
Main Methods:
- Review of recently developed viral-vector based antigen delivery systems.
- Inclusion of attenuated virus, DNA, and RNA viral vectors.
- Focus on vaccine testing in veterinary species.
Main Results:
- Viral-vector based ADSs represent a promising approach for developing effective vaccines against viral epizootic diseases.
- These systems are valuable for studying species-specific protective immunity.
- ADSs facilitate the exploration of modulating immune mechanisms.
Conclusions:
- Viral-vector based ADSs are crucial for advancing veterinary vaccinology.
- These systems offer powerful tools for immunological research in different species.
- Future applications include potentiating protective immune responses against viral diseases.
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