Evolutionary patterns in prokaryotic genomes
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Updated: Jun 29, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
1UPMC Univ Paris 06, Atelier de BioInformatique, F-75005 Paris, France. erocha@pasteur.fr
Abstract:
Prokaryotic genomics is shifting towards comparative approaches to unravel how and why genomes change over time. Both phylogenetic and population genetics approaches are required to dissect the relative roles of selection and drift under these conditions. Lineages evolve adaptively by selection of changes in extant genomes and the way this occurs is being explored from a systemic and evolutionary perspective to understand how mutations relate with gene repertoire changes and how both are contextualized in cellular networks. Through an increased appreciation of genome dynamics in given ecological contexts, a more detailed picture of the genetic basis of prokaryotic evolution is emerging.
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