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RecA protein in the SOS response: milestones and mysteries
1Waksman Institute of Microbiology, Rutgers State University of New Jersey, Piscataway 08854.
Biochimie
|February 1, 1991
Abstract:
The role of RecA protein in the SOS response of Escherichia coli is traced from the isolation of the first recA mutant to our current understanding of the scope and regulation of this DNA damage-inducible system. In addition, possible RecA protein activities that may be essential in the expression of several SOS phenotypes (stable DNA replication, DNA replication recovery, SOS mutagenesis and RecA association with the cell membrane) are discussed.