The clinical features and treatment of pediatric intracranial aneurysm

Jiantao Liang1, Yuhai Bao, Hongqi Zhang

  • 1Cerebrovascular Diseases Research Institute, Capital Medical University, 45 Changchun Street, Beijing 100053, China.

Insights

Pediatric intracranial aneurysms are rare but differ from adult cases. Both endovascular and microsurgical treatments are effective, with endovascular therapy often preferred for complex pediatric aneurysms, leading to favorable outcomes.

Area of Science:

  • Neurology
  • Pediatric Neurosurgery
  • Vascular Neurology

Background:

  • Intracranial aneurysms are uncommon in children.
  • Understanding their unique characteristics is crucial for effective management.

Purpose of the Study:

  • To detail the clinical and radiological features of pediatric intracranial aneurysms.
  • To evaluate therapeutic outcomes and guide treatment strategies.

Main Methods:

  • Retrospective analysis of 24 pediatric patients (<14 years) treated over 23 years.
  • Review of diagnosis, treatment modalities (endovascular, microsurgical, conservative), and outcomes.

Main Results:

  • Posterior circulation and giant aneurysms were common (36% and 32%).
  • Subarachnoid hemorrhage occurred in 46% of patients.
  • 92% of patients achieved favorable outcomes with various treatments.

Conclusions:

  • Pediatric intracranial aneurysms exhibit distinct features compared to adults, including higher rates of giant and posterior circulation aneurysms.
  • Both endovascular and microsurgical approaches are effective.
  • Endovascular therapy is often the optimal choice for complex pediatric aneurysms.
Abstract

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...