[Acute coronary syndromes]
1Pôle cardiovasculaire et métabolique, CHU Rangueil, 31059 Toulouse Cedex, France. elbaz.m@chu-toulouse.fr
Insights
Chest pain requires immediate evaluation as a potential acute coronary syndrome (ACS). Prompt diagnosis and reperfusion therapy, especially for ST-elevation myocardial infarction (STEMI), are crucial for patient survival and prognosis.
Area of Science:
- Cardiology
- Emergency Medicine
Context:
- Chest pain is a critical symptom requiring immediate assessment for acute coronary syndromes (ACS).
- Acute coronary syndromes encompass ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI).
- Timely diagnosis and intervention significantly impact patient outcomes.
Purpose:
- To outline the diagnostic and treatment strategies for acute coronary syndromes.
- To differentiate between STEMI and NSTEMI and their respective emergency management protocols.
- To emphasize the importance of risk factor control for long-term patient prognosis.
Summary:
- STEMI necessitates emergency diagnosis and reperfusion therapy (thrombolysis or angioplasty) for optimal survival.
- NSTEMI diagnosis relies on ECG monitoring, troponin testing, and clinical context, with angioplasty considered less frequently as an emergency.
- Initial treatment for confirmed ACS involves combined antiplatelet and anticoagulant therapy, with long-term management focused on cardiovascular risk factor control.
Impact:
- Establishes a clear diagnostic and treatment pathway for acute coronary syndromes.
- Highlights the critical role of rapid reperfusion in improving survival rates for STEMI patients.
- Underscores the importance of patient education and risk factor modification for preventing recurrent cardiovascular events.
Abstract:
Given how serious coronary pathologies can be, any chest pain must automatically be considered as an acute coronary syndrome. This single term covers acute coronary syndromes with elevation of the ST segment, conventionally called STEMI. They have to be treated as emergencies for diagnosis and treatment. Reperfusion by thrombolysis or angioplasty is carried out without delay in the framework defined by the recommendations. The survival and functional prognosis of the patient depend on how quickly reperfusion is started and how successful it is. Acute coronary syndromes without ST segment elevation are called NSTEMI. They are only rarely considered as emergency cases for angioplasty. The diagnosis, which may sometimes be difficult, is based on hospital monitoring of the electrocardiogram, repeated troponin tests, and the patient's clinical context (prior coronary revascularization, renal failure, diabetes ...). Depending on tropinin levels, NSTEMI are divided into tropinin+ NSTEMI (with raised tropinin levels) and tropinin- NSTEMI (without raised tropinin level). Treatment for acute coronary syndromes, ST+ and NST (with confirmed or highly probable coronary origin), should initially include an association of antiplatelet and anticoagulant treatment, which will be continued if the coronary origin is confirmed. The long-term prognosis for the patient will be largely dependent on education and the control of cardiovascular risk factors. Acute coronary syndrome (ACS) groups together all the clinical manifestations previously subdivided into myocardial infarction, (transmural or rudimentary) and various categories of unstable angina manifestations.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome V: Nursing Management
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome IV: Interprofessional Care


